Inhibition of catechol-O-methyltransfera
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Thomas Müller; Christoph Erdmann; Siegfried Muhlack; Dirk Bremen; Horst Przuntek
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Article
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2005
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John Wiley and Sons
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English
⚖ 78 KB
## Abstract The short plasma half‐life limits the antiparkinsonian efficacy of levodopa/carbidopa (LD/CD). Administration of LD/CD with the catechol‐__O__‐methyltransferase inhibitor entacapone in one tablet (LCE) may extend plasma half‐life of LD and thus its effect on motor symptoms in patients w