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Effect of lanthanum ions on the lipid polymorphism of phosphatidylethanolamines

✍ Scribed by Fen Hwang; Da-qing Zhao; Jian-wen Chen; Xiao-hong Chen; Jia-zuan Ni

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 273 KB
Volume: 82
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(96)02561-3

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✦ Synopsis

The influence of lanthanum ions on the polymorphic phase of egg phosphatidylethanolamine and dielaidoylphosphatidylethanolamine (PE and DEPE) has been investigated by means of 31p-nuclear magnetic resonance (31p-NMR) and high sensitivity differential scanning calorimetry (DSC) techniques. 3~p-NMR experiments show that lanthanum ions promote the formation of the hexagonal II phase at temperatures lower than those of the pure egg PE. DSC results also show that lanthanum ions induce the formation of hexagonal II phase in DEPE liposomes even at very low ion concentration. The effect of lanthanum ions on the polymorphism of PE liposomes is much greater than that of calcium.

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