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Effect of L-α-amino-γ-guanidinobutyric acid on melphalan therapy of the L1210 murine leukemia

✍ Scribed by Vistica, David T.; Rabon, Anne; Rabinovitz, Marco

Book ID
122391710
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
258 KB
Volume
6
Category
Article
ISSN
0304-3835

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The L1210 tumor system was used in vitro and in vivo in comparative studies with activated cyclophosphamide analogs, cyclophosphamide and phosphoramide mustard. All the above compounds gave substantial cell kills (5 logs) of L1210 in vivo at doses that were non-toxic, but slight differences were not