The comporative effects of flurazepam, clorazepate, L-dopa, and thyrotropin-releasing hormone (TRH) on REM sleep were investigated in normal, healthy adults. A single dose of each drug was given orally to the subjects 30 min before bedtime. A dose of 30 mg flurazepam significantly decreased REM slee
β¦ LIBER β¦
Effect of L-Dopa on the Sleep of Man
β Scribed by WYATT, RICHARD J.; CHASE, THOMAS N.; SCOTT, JIMMY; SNYDER, FREDERICK; ENGLEMAN, KARL
- Book ID
- 109676383
- Publisher
- Nature Publishing Group
- Year
- 1970
- Tongue
- English
- Weight
- 502 KB
- Volume
- 228
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/228999a0
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## Abstract The putative role of the dopaminergic system in sleep bruxism (SB) was studied in a doubleβblind clinical trial by using low doses of shortβterm Lβdopa in combination with benserazide. We recorded 10 patients with SB in our sleep laboratory for 3 consecutive nights. The first night was