✦ LIBER ✦

Effect of kolanut on the pharmacokinetics of the antimalarial drug halofantrine

✍ Scribed by Yetunde T. Kolade; Chinedum P. Babalola; Ajibola A. Olaniyi; Gerhard K. E. Scriba

Publisher: Springer
Year: 2007
Tongue: English
Weight: 112 KB
Volume: 64
Category: Article
ISSN: 0031-6970
DOI: 10.1007/s00228-007-0387-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics of the diastereomers of

Pharmacokinetics of the diastereomers of arteether, a potent antimalarial drug, in rats

✍ S. Sabarinath; K. P. Madhusudanan; R. C. Gupta 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB

The influence of lipids on stereoselecti

The influence of lipids on stereoselective pharmacokinetics of halofantrine: Important implications in food-effect studies involving drugs that bind to lipoproteins

✍ Dion R. Brocks; Kishor M. Wasan 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 119 KB 👁 1 views

The objective of this study was to determine the effect of lipids on the pharmacokinetics of halofantrine enantiomers. Rats were given (+/-)-halofantrine HCl 2 mg/kg i.v., or 7 mg/kg orally. Some rats were rendered hyperlipidemic by intraperitoneal administration of poloxamer 407 1 g/kg, followed by

Direct determination of the enantiomers

Direct determination of the enantiomers of the antimalarial drug halofantrine and its active metabolite N-desbutylhalofantrine in human plasma

✍ H. Terefe; G. Blaschke 📂 Article 📅 1994 🏛 Elsevier Science ⚖ 245 KB

Effect of psychotropic drugs on the phar

Effect of psychotropic drugs on the pharmacokinetics of lithium

✍ N. N. Samoilov; B. I. Lyubimov; V. M. Sholokhov; V. M. Petrov 📂 Article 📅 1980 🏛 Springer US 🌐 English ⚖ 207 KB

The effects of impaired organ functionin

The effects of impaired organ functioning on the pharmacokinetics of drugs

✍ Hekster, Y. A. ;Vree, T. B. 📂 Article 📅 1987 🏛 Springer 🌐 Dutch ⚖ 87 KB

Pharmacokinetics of halofantrine in the

Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons

✍ Dion R. Brocks; Jason W. Toni 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB 👁 2 views

The antimalarial drug, halofantrine, is chiral and is administered clinically as the racemate. In order to define the pharmacokinetic properties of halofantrine enantiomers in the rat, male Sprague-Dawley rats (264-311 g) were given halofantrine HCl orally (n = 5; 14 mg/kg) or intravenously (i.v.) (