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Effect of ischemia and hypoxia on rat brain glycolipids

✍ Scribed by Dr. K. Domańska-Janik; J. Strosznajder; T. Zalewska

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
450 KB
Volume
7
Category
Article
ISSN
0360-4012

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✦ Synopsis

Abstract

Hypoxia and ischemia produced the changes in the rat brain lipid composition. Moderate decreases in the content of phospholipids, cerebrosides, and gangliosides were observed. Three different experimental models of oxygen deficiency varied as to the degree of energy disturbances were correlated with their effect on the particular lipid classes. The decrease of cerebrosides content, but not gangliosides and phospholipids, could be attributed directly to energy disturbances and concomitant restriction of glucose supply to the hypoxic‐ischemic brain.

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