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Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine

✍ Scribed by Hye-Won Chae; In-Wha Kim; Hyo-Eon Jin; Dae-Duk Kim; Suk-Jae Chung; Chang-Koo Shim


Book ID
107641961
Publisher
Springer
Year
2008
Tongue
English
Weight
199 KB
Volume
31
Category
Article
ISSN
0253-6269

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Effect of bile salts on the transport of
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Bile salts are known to enhance the permeability of biological barriers but little is known about their effects on drug permeability across the blood-brain barrier (BBB). In this paper, the rat brain endothelial 4 (RBE4) cell monolayer incubated with astrocyte-conditioned medium was used as an in vi