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Effect of intra-ischemic hypothermia on the expression of c-Fos and c-Jun, and DNA binding activity of AP-1 after focal cerebral ischemia in rat brain

✍ Scribed by Kazunori Akaji; Sadao Suga; Tadahiro Fujino; Keita Mayanagi; Joji Inamasu; Takashi Horiguchi; Shuzo Sato; Takeshi Kawase

Book ID
113999407
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
621 KB
Volume
975
Category
Article
ISSN
0006-8993

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Administration of convulsant doses of Metrazole (pentylenetetrazol) and picrotoxin, as well as maximal electroshock, results in a rapid but transient increase in c-fos mRNA in mouse brain. Elevation of c-fos mRNA is followed by the accumulation and subsequent disappearance of Fos, the protein encode