Effect of internal diffusional restrictions on kinetic parameters of hydrolysis of penicillin G and synthesis of cephalexin with immobilized penicillin acylase
β Scribed by A. Illanes; P. Valencia; L. Wilson
- Book ID
- 108218292
- Publisher
- Elsevier
- Year
- 2009
- Tongue
- English
- Weight
- 85 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1871-6784
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## Abstract The kinetic parameters for penicillin G hydrolysis in systems with penicillin G acylase from __Escherichia coli__ (free and immobilized on activated chitosan microbeads produced by electrostatic extrusion) were determined. The obtained kinetic results indicated that both systems (free a
## Abstract The effects of organic cosolvents on the synthesis of ampicillin from phenylglycine methyl ester (PGME) and 6βamino penicillanic acid (6βAPA) using immobilized __Bacillus megaterium__ penicillin G acylase have been examined. Several cosolvents were tested for their influence on the enzy