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Effect of interleukin 2 on fetal thymocytes in organ cultures: Generation of lymphokine-activated killer cells

โœ Scribed by Margot Skinner; John Marbrook


Book ID
113134173
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
537 KB
Volume
112
Category
Article
ISSN
0008-8749

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Induction of lymphokine-activated killer
โœ Hisatoshi Imaya; Hiroshi Matsuura; Motoshige Kudo; Shozo Nakazawa ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 405 KB

Using a 4-h 51Cr release assay, we observed that thymocytes from Fischer strain rats incubated with recombinant human interleukin-2 (rhIL-2) developed cytotoxicity to YAC-1 lymphoma, 9L-glioma, and B-16 melanoma cells (effector/target ratio = 25/1). Induction of the lymphokine-activated killer (LAK)