Effect of inhibitors on histamine release from mast cells recovered by bronchoalveolar lavage in Basenji-Greyhound and Mongrel dogs

Inhibitory effects of rupatadine on mast

Inhibitory effects of rupatadine on mast cell histamine release and skin wheal development induced by Ascaris suum in hypersensitive dogs

✍ Mireia Queralt; Pilar Brazís; Manuel Merlos; Anna Puigdemont 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

The present studies were performed to compare the cutaneous antiallergic effects of rupatadine, a new potent dual antagonist of histamine and platelet-activating factor (PAF), with those of loratadine (an H 1 -antihistamine) and SR-27417A (a PAF antagonist). Two experimental models were used: an in