Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors

Different effects of anti-sonic hedgehog

Different effects of anti-sonic hedgehog antibodies and the hedgehog pathway inhibitor cyclopamine on generation of dopaminergic neurons from neurospheres of mesencephalic precursors

✍ J.A. Parga; J. Rodriguez-Pallares; V. Blanco; M. J. Guerra; J. L. Labandeira-Gar 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB

## Abstract Production of dopaminergic neurons from stem/precursor cells for transplantation in Parkinson's disease has become a major focus of research. However, the inductive signals mediating this process have not been clarified. Reported data on the effects of Sonic hedgehog on differentiation