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Effect of INCB018424, a JAK1 and JAK2 inhibitor, on senescence phenotype in old mice

✍ Scribed by Mezera, V.; Tchkonia, T.; Pirtskhalava, T.; White, T.; Kirkland, J.L.

Book ID
122474774
Publisher
Elsevier
Year
2013
Tongue
English
Weight
61 KB
Volume
4
Category
Article
ISSN
1878-7649

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## Abstract ## BACKGROUND: Symptomatic burden from constitutional symptoms, anemia, and splenomegaly‐related symptoms are common and morbidity inducing in patients with myelofibrosis (MF). The authors previously developed a MF‐specific instrument for capturing the burden of MF‐associated disease‐r