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Effect of in vivo HeNe laser irradiation on biogenic amine levels in rat brain

✍ Scribed by M.C. Cassone; A. Lombard; V. Rossetti; R. Urciuoli; P.M. Rolfo

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
391 KB
Volume
18
Category
Article
ISSN
1011-1344

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✦ Synopsis

In order to elucidate the metabolic modifications induced in rat brain by low power He-Ne laser irradiation in vivo, the variations in the biogenic amine levels in cortex, striatum and hippocampus were studied. Noradrenaline (NA), dopamine (DA) and serotonin (5-HT) were evaluated by HPLC-EC on irradiated rats, untreated rats (controls) and rats which had undergone restraint stress (stressed). The results obtained on groups of four to eight rats assayed individually showed that irradiation caused a strong increase in 5-HT in striatum and hippocampus, a small but significant decrease in NA in cortex, and DA levels were not significantly affected. Restraint stress per se led to a considerable decrease in 5-HT and DA in striatum and hippocampus, but did not significantly alter the NA levels.

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