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EFFECT OF ICAM-1 POLYMORPHISM ON ENDOTHELIAL CELLS IN VITRO

✍ Scribed by Charlotte Lawson; Angela Holder; Marlene Rose

Book ID
116342174
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
39 KB
Volume
13
Category
Article
ISSN
1054-8807

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Endothelial cells, as they normally exist in the vasculature as quiescent cells, perform several functions. In an inflammatory response, endothelial cells are activated to up-regulate a number of genes, including E-selectin (ELAM-l), VCAM-1, ICAM-1, interleukin (IL)-l, IL-8 and plasminogen activator