Effect of hyperbaric oxygen on GABA transport in rat brain synaptosomes
β Scribed by D. D. Wheeler; J. G. Blackburn; J. J. Tai
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 777 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1435-1463
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## Abstract The sodium dependence of Ξ³βaminobutyric acid (GABA) uptake has been studied in rat hypothalamic synaptosomes, and the results compared to previous studies in cortical synaptosomes. Initial velocity of GABA uptake was measured as a function of both GABA and sodium concentration, and thes
Pretreatment of isolated brain synaptic endings with commercial phospholipase A, isolated from venom of Apis mellifera, followed by a BSA washing, selectively inhibited the depolarization-dependent portion of 45Ca uptake. Phospholipase A, initially caused an increase of synaptosome respiration and