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Effect of hydroxyurea and normal plasma on DNA synthesis in lymphocytes from Fanconi anemia patients

✍ Scribed by Sara Frias; Laura Gómez; Bertha Molina; Emilio Rojas; Patricia Ostrosky-Wegman; Alessandra Carnevale


Book ID
113194982
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
653 KB
Volume
357
Category
Article
ISSN
0027-5107

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Effects of alkylating agents on lymphocy
✍ Božena Novotná; Petr Goetz; Naděžda I. Surkova 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 418 KB

The frequency of sister chromatid exchanges (SCE) and chromosome aberrations and the dynamics of cell division in peripheral blood lymphocytes of four patients with Fanconi's anemia were studied after in vitro exposure to alkylating agents TEPA and mitomycin. SCE frequency was significantly increase