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Effect of human B-endorphin on the binding of different opiates to mouse brain membranes

✍ Scribed by J. Garzón; P. Sánchez-Blázquez; N.M. Lee

Book ID
118942013
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
184 KB
Volume
33
Category
Article
ISSN
0024-3205

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Binding of synthetic peptide TPLVTLFK to
Binding of synthetic peptide TPLVTLFK to nonopioid beta-endorphin receptor on rat brain membranes
✍ Yuliia N. Nekrasova; Vladimir B. Sadovnikov; Yury A. Zolotarev; Elena V. Navolot 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 129 KB

## Abstract The synthetic peptide TPLVTLFK corresponding to the sequence 12–19 of β‐endorphin (referred to as octarphin) was found to bind to high‐affinity naloxone‐insensitive binding sites on membranes isolated from the rat brain cortex (__K__~d~ = 2.6 ± 0.2 nM). The binding specificity study rev