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Effect of Hormones on Growth Rates of Malignant and Nonmalignant Human Mammary Epithelia in Cell Culture

✍ Scribed by Paula Klevjer-Anderson and Gertrude Case Buehring

Book ID
125618414
Publisher
Society for In Vitro Biology
Year
1980
Tongue
English
Weight
588 KB
Volume
16
Category
Article
ISSN
1475-2689

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Normal human breast tissue was enzymatically dissociated and the cells were injected into the gland-free fat-pads of athymic nude mice. Within 30 days, small, spherical, duct-like epithelial elements (organoids) formed in 68% of the fat-pads inoculated (0-23 organoidslfat-pad). Short-term (30-day) t