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Effect of honokiol on activity of GAD65 and GAD67 in the cortex and hippocampus of mice

✍ Scribed by Tien-Hsiung Ku; Yih-Jing Lee; Su-Jane Wang; Chen-Hua Fan; Lu-Tai Tien


Book ID
113848847
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
474 KB
Volume
18
Category
Article
ISSN
0944-7113

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## Abstract γ‐Aminobutyric acid (GABA), the principal inhibitory neurotransmitter of CNS, has been consistently implicated in the pathophysiology of schizophrenia. GABA is synthesized from glutamate by the enzyme glutamic acid decarboxylase (GAD). Two isoforms of GAD have been identified and have b