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Effect of High Pressure on the Polymorphs of Paracetamol

✍ Scribed by E. V. Boldyreva; T. P. Shakhtshneider; H. Ahsbahs; H. Sowa; H. Uchtmann


Book ID
110345228
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
170 KB
Volume
68
Category
Article
ISSN
0022-5215

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A high pressure differential scanning calorimeter (HP-DSC) has been used to investigate the pressure dependence of the melting of the monoclinic (Form I) and orthorhombic (Form II) polymorphs of paracetamol (acetaminophen). DSC scans obtained at ambient pressure show that the stable monoclinic form