Effect of high-dose epinephrine on regional blood flow during CPR in a porcine model

✍ Scribed by CG Brown; HA Werman; RL Hamlin; J Ashton

• Publisher: Elsevier Science
• Year: 1985
• Tongue: English
• Weight: 140 KB
• Volume: 14
• Category: Article
• ISSN: 1097-6760
• DOI: 10.1016/s0196-0644(85)80384-x

✦ Synopsis

ABSTRACTS

time from the venipuncture until availability of serum drug level was 2.13 +_ 0.88 hours in Group 1 and 0.45 _+_+ 0.35 hours in Group 2 (P < .001). Based on initial pulse, respiratory rate, and the physician's estimate of respiratory distress, Group 2 patients were somewhat more ill than Group 1 patients on arrival. However, ED treatment times were comparable for the two groups. Reliability of the Seralyzer was excellent. All Seralyzer determinations were within 3.6 mg/dL of the laboratory level. The Seralyzer allowed for an early, accurate loading dose of theophylline. Placement of an Ames Seralyzer in the ED will result in rapid assessment of serum theophylline levels, markedly improve patient care, and decrease the probability of aminophylline toxicity.