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Effect of hexadecane on the pharmacokinetics of hexachlorobenzene

✍ Scribed by E. Scheufler; K. Rozman

Book ID
113206332
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
619 KB
Volume
75
Category
Article
ISSN
0041-008X

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In female rats dosed orally with 14C-hexachlorobenzene the extent of intestinal absorption of carbon-14 has been found to be dependent on the form of application. When the substance was given as a solution in oil about 80% of the dose administered was absorbed, but when given as an aqueous suspensio

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✍ K. Rozman; T. Rozman; H. Greim πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 325 KB

## Abstract The effect of hexadecane on the intestinal excretion of hexachlorobenzene was studied in female Sprague‐Dawley rats dosed twice with ^14^C‐hexachlorobenzene at 50 mg kg^βˆ’1^ per os. Injection of 75 mg __n__‐hexadecane into ligated and unligated segments of the intestine increased concent