✦ LIBER ✦

Effect of herpes simplex virus on human embryonic cells latently infected with reovirus type 3

✍ Scribed by Thomas M. Bell; Germano M. R. Munube; E. R. Griffin

Publisher: John Wiley and Sons
Year: 1968
Tongue: French
Weight: 691 KB
Volume: 3
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910030608

No coin nor oath required. For personal study only.

✦ Synopsis

A persistent latent infection of human embryo fibroblasts by reovirus type 3 was found to be due to the continuous infection of a small proportion of the cells. Superinfection of these cultures by herpes simplex virus resulted in the destruction of the monolayers by the herpes virus without any obvious signs of interference.

Electron microscopic examination of these doubly infected cultures showed the presence of multi-nucfear blebs and an unusual, " condensed-mass ", form of intranuclear herpes virus. The implications of these findings are discussed.

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