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Effect of Grapefruit Juice, Naringin, Naringenin, and Bergamottin on the Intestinal Carrier-Mediated Transport of Talinolol in Rats

โœ Scribed by de Castro, Whocely Victor; Mertens-Talcott, Susanne; Derendorf, Hartmut; Butterweck, Veronika


Book ID
127358569
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
172 KB
Volume
56
Category
Article
ISSN
0021-8561

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โœ John S. Grundy; Lise A. Eliot; Ken M. Kulmatycki; Robert T. Foster ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 157 KB ๐Ÿ‘ 2 views

Previous studies with rats indicate that nifedipine undergoes both hepatic and extrahepatic presystemic metabolism after peroral (po) administration, and that its bioavailability is increased and absorption delayed by concomitant administration of grapefruit juice concentrate (GJC). Hence, the effec