Eighteen surgical patients were studied to determine the effect of anesthesia (general or spinal) and surgery on serum and urinary colony-stimulating factor(s) (CSF). CSF is a leukopoietin that stimulates proliferation of macrophages and granulocytes from bone marrow precursor cells. CSF was assayed
Effect of granulocyte-macrophage colony-stimulating factor on treatment of acute osteomyelitis
✍ Scribed by M. Subasi; Ahmet Kapukaya; Cumhur Kesemenli; Halil Kaya; Ibrahim Sarı
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 88 KB
- Volume
- 121
- Category
- Article
- ISSN
- 1434-3916
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GM-CSF is a major regulator of myelopoiesis. Recombinant human GM-CSF (250 micrograms/m2 per day i.v.) was used prior to chemotherapy ("3 + 7" scheme) to recruit leukemic blasts in vivo (de novo AML patients, n = 20) into the chemotherapy sensitive phases of the cell cycle. The stimulatory effect of
## Abstract We previously established 2 lung cancer cell lines, OKa‐C‐1 and MI‐4, which constitutively produce an abundant dose of granulocyte‐colony stimulating factor (G‐CSF) and granulocyte macrophage‐colony stimulating factor (GM‐CSF). Many other cases with G‐CSF or GM‐CSF producing tumors have