Primary cultures of rat hippocampal neurons were prepared and exposed to increasing concentrations of a peroxyl radical-generator, 2,2′-azobis 2 amidinopropane (AAPH). Addition of AAPH (20 or 50 mM) to the medium caused a decrease in cell viability and an increase in the number of apoptotic cells. V
✦ LIBER ✦
Effect of Ginkgo biloba (EGb 761) on staurosporine-induced neuronal death and caspase activity in cortical cultured neurons
✍ Scribed by Lourdes Massieu; Julio Morán; Yves Christen
- Book ID
- 113499419
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 460 KB
- Volume
- 1002
- Category
- Article
- ISSN
- 0006-8993
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## Abstract This study investigated the potential neuroprotective effects of the __Ginkgo biloba__ extract, EGb‐761, and ginkgolide B, on adrenalectomy (ADX)‐induced cell death in the dentate gyrus (DG). Adrenalectomised, sham surgery‐treated, and naive controls received either EGb‐761 (25, 50, or