Effect of geometrical structure on the in vivo quality change of a three-dimensionally perforated porous bone cell scaffold made of apatite/collagen composite

Effect of geometrical structure on drug

Effect of geometrical structure on drug release rate of a three-dimensionally perforated porous apatite/collagen composite cement

✍ Makoto Otsuka; Hidenori Nakagawa; Atsuo Ito; William I. Higuchi 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB

To improve the biocompatibility, inter-connective pore structure, and drug delivery ability of self-setting apatite/collagen composite cement (ACC), a three-dimensionally perforated porous apatite/collagen composite cement (TPPACC) containing 3% indomethacin (IMC) was obtained in an arranged multi-c