Effects of excipients on hydrate formati
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Sari Airaksinen; Pirjo Luukkonen; Anna JΓΈrgensen; Milja Karjalainen; Jukka Ranta
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Article
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2003
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John Wiley and Sons
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English
β 326 KB
Transformations between solid phases in dosage forms can lead to instability in drug release. Thus, it is important to understand mechanisms and kinetics of phase transformations and factors that may influence them. During wet granulation theophylline shows pseudopolymorphic changes that may alter i