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Effect of genetic background and culture conditions on the production of herpesvirus-based gene therapy vectors

✍ Scribed by Ali Ozuer; James B. Wechuck; William F. Goins; Darren Wolfe; Joseph C. Glorioso; Mohammad M. Ataai


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
216 KB
Volume
77
Category
Article
ISSN
0006-3592

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## Abstract The production of gene therapy retroviral vectors presents many difficulties, mainly due to vector instability and low cell productivities hampering the attainment of high titers of infectious viral vectors. The objective of this work is to increase the production titers of retroviral v