Effect of furosemide on insulin and glucagon responses to arginine in normal subjects
โ Scribed by D. Giugliano; R. Torella; S. Sgambato; F. D'Onofrio
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 324 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0012-186X
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๐ SIMILAR VOLUMES
An excessive glucagon secretion to intravenous arginine infusion was found in obese hyperinsulinaemic patients with glucose intolerance. This study was designed to determine whether the glucagon hyperresponsiveness to arginine in these patients would improve by insulin infused at a high enough dose
The effects of glucose and arginine on insulin secretion in the presence of glucagon antibodies were investigated in rats in vivo. In contrast to controls, animals given glucagon antibodies showed an inhibition of arginine-stimulated (p less than 0.001), but not glucose-stimulated, insulin secretion