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Effect of fluvastatin on apoptosis in human CD4+ T cells

✍ Scribed by Karen Thursday R. Samson; Kenji Minoguchi; Akihiko Tanaka; Naruhito Oda; Takuya Yokoe; Shinji Okada; Yoshitaka Yamamoto; Yoshio Watanabe; Mayumi Yamamoto; Shin Ohta; Mitsuru Adachi

Book ID
113526898
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
446 KB
Volume
235
Category
Article
ISSN
0008-8749

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## Abstract We have previously shown that inhibition of the proteolytic activity of the proteasome induces apoptosis and suppresses essential functions of activated human CD4^+^ T cells, and we report now the detailed mechanisms of apoptosis following proteasome inhibition in these cells. Here we s