Treatment of lactic acidosis: effects of
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I. Okabe; H. Kodama; H. Shimoizumi; S. Kamoshita; S. Miyabayashi
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Article
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1986
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Springer
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English
β 89 KB
Sir: Dichloroacetate (DCA, 15-20 mg/kg per day) was given orally twice daily to a 12-mouth-old boy with congenital lactic acidosis [1,3]. The clinical and laboratory findings were compatible with Leigh syndrome [2]. Enzyme activities associated with lactate metabolism were normal in his fibroblasts