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Effect of extremely-low-frequency pulsed magnetic fields on the mitogenic response of peripheral blood mononuclear cells

✍ Scribed by Dr. Nuala A. Mooney; Roy E. Smith; Bernard W. Watson

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 470 KB
Volume: 7
Category: Article
ISSN: 0197-8462
DOI: 10.1002/bem.2250070406

No coin nor oath required. For personal study only.

✦ Synopsis

The effect of extremely-low-frequency pulsed magnetic fields (PMF) on the response of human peripheral blood mononuclear cells to mitogenic stimulation is reported. We investigated 25 healthy control subjects. Mitogen-stimulated mononuclear cells were exposed to PMF for 72 h and an inhibition of 'H-thymidine uptake was observed in all but one subject. The degree of inhibition of 3H-thymidine uptake was as much as 60%. There was no significant difference between the blastogenic responses of mononuclear cells exposed to PMF for 12 h and control cultures. This study establishes an inhibitory effect of PMF on an in vitro measure of immune function.

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