Fast chiral separation of drugs using co
Fast chiral separation of drugs using columns packed with sub-2 μm particles and ultra-high pressure
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Davy Guillarme; Gregoire Bonvin; Flavia Badoud; Julie Schappler; Serge Rudaz; Je
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Article
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2009
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John Wiley and Sons
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English
⚖ 333 KB
## Abstract The use of columns packed with sub‐2 μm particles in liquid chromatography with very high pressure conditions (known as UHPLC) was investigated for the fast enantioseparation of drugs. Two different procedures were evaluated and compared using amphetamine derivatives and β‐blockers as m