Effects of stabilizers on the destabiliz
Effects of stabilizers on the destabilization of proteins upon adsorption to aluminum salt adjuvants
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Peek, Laura J. (author);Martin, Talia T. (author);Nation, Charity Elk (author);P
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Article
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2007
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John Wiley and Sons Inc.
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English
β 267 KB
Excipients for protein-based vaccines are currently identified by evaluating the stability of the protein in solution. In most cases, however, the protein is adsorbed to the surface of an aluminum salt adjuvant in the final vaccine formulation. Previous studies showed that model protein antigens may