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Effect of Excipients on Acetaminophen Metabolism and Its Implications for Prevention of Liver Injury

✍ Scribed by Ganetsky, Michael; Böhlke, Mark; Pereira, Luis; Williams, David; LeDuc, Barbara; Guatam, Shiva; Salhanick, Steven D.

Book ID
121194040
Publisher
Sage Publications
Year
2013
Tongue
English
Weight
436 KB
Volume
53
Category
Article
ISSN
0091-2700

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Effect of salicylamide and acetaminophen on dextromethorphan hydrobromide metabolism: Possible pharmacological implications
✍ Gollamudi Ramachander; Florence D. Williams; Jane Frances Emele 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 520 KB

The effect of salicylamide and acetaminophen on the metabolic fate of dextrorphan, the primary metabolite of dextromethorphan, was studied in vivo in the rat. Plasma dextrorphan levels were measured at 5-min intervals up to 20 min and at longer intervals up to 2 hr after dextromethorphan hydrobromid