The role of changes in blood-brain barrier permeability in the pathogenesis of hepatic encephalopathy remains uncertain. To test the hypothesis that brain microvessel permeability is nonselectively increased in hepatic encephalopathy we measured the blood-brain barrier permeability-surface area prod
โฆ LIBER โฆ
Effect of ethimizole on permeability of the blood-cell barrier in carbon tetrachloride-poisoning-induced hepatitis
โ Scribed by V. E. Neiko
- Publisher
- Springer US
- Year
- 1980
- Tongue
- English
- Weight
- 199 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-4888
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Methotrexate was administered by intraperitoneal injection (100 mg/kg) to unirradiated mice, and to mice receiving varying doses of cranial irradiation. The animals were sacrificed 24 hours after injection, and methotrexate assays were performed on brain tissue. No methotrexate was detected in the