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Effect of Erythropoietin Axotomy-Induced Apoptosis in Rat Retinal Ganglion Cells

✍ Scribed by Weishaupt, J. H.

Book ID
120234285
Publisher
Association for Research in Vision and Ophthalmology
Year
2004
Tongue
English
Weight
324 KB
Volume
45
Category
Article
ISSN
0020-9988

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Adenoviral-mediated transfer of ciliary neurotrophic factor (CNTF) to the retina rescued retinal ganglion cells (RGCs) from axotomy-induced apoptosis, presumably via activation of the high affinity CNTF receptor alpha (CNTFRalpha) expressed on RGCs. CNTF can also activate astrocytes, via its low aff