Effect of erythrocytes on the hepatic distribution kinetics of antipyrine
β Scribed by Selma Sahin; Malcolm Rowland
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 635 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0378-7966
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π SIMILAR VOLUMES
Following an overnight fast and 2 days of abstention from caffeine, a single 1.0-g oral dose of antipyrine was administered to 20 obese but otherwise healthy subjects (group A) and 11 healthy volunteers (group B). Weight, Body Mass Index (BMI) and % of Ideal Body Weight (IBW) were significantly grea
A group of 15 rats received two intravenous bolus doses of antipyrine (15 mg/kg) separated by a 57 hour infusion (with bolus dose) of phenobarbital. Phenobarbital bolus doses and infusion rates were based on a preliminary pharmacokinetic study (7 rats) and were varied to achieve a broad range of ste