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Effect of Enzyme Induction and Inhibition on the Fate of Metronidazole and Tinidazole in the Rat

✍ Scribed by Männistö, P. T. ;Saijonmaa, O. ;Haataja, H.


Book ID
114800932
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
421 KB
Volume
60
Category
Article
ISSN
0901-9928

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Using two UV-spectrophotometric methods, the hydrolysis of tinidazole was studied at pH 1.00-8.45 at 80 degrees C. The reaction followed apparent first-order kinetics throughout the studied range. No kinetic salt effect was detected, indicating that at least one of the reacting partners forming the