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Effect of edge activators on the formation and transfection efficiency of ultradeformable liposomes

✍ Scribed by Eun Hye Lee; Adele Kim; Yu-Kyoung Oh; Chong-Kook Kim

Book ID
108069337
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
226 KB
Volume
26
Category
Article
ISSN
0142-9612

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## Abstract ## Background Control of the structure and physicochemical properties of DNA complexed with nonviral vectors is essential for efficient biodistribution and gene delivery to cells. Cationic liposomes interact with DNA giving transfection competent but large and heterogeneous aggregates.