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Effect of drugs inhibiting spermidine biosynthesis and metabolism on the in vitro development ofPlasmodium falciparum

โœ Scribed by A. Kaiser; A. Gottwald; C. Wiersch; B. Lindenthal; W. Maier; H. Seitz


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
209 KB
Volume
87
Category
Article
ISSN
1432-1955

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Effect of dihomogammalinolenic acid and
โœ L. Iversen; K. Fogh; K. Kragballe ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 478 KB

The purpose of the present study was to determine the effect of the n-6 fatty acid, dihomogammalinolenic acid (DGLA, 20 : 3, n-6) on arachidonic acid (AA) (C20:4) metabolism by human peripheral mononuclear leukocytes (HPML). After incubation of HPML with A23187 (5 ~tM) and DGLA, the cyclooxygenase (