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Effect of doxycycline-regulated calnexin and calreticulin expression on specific thrombopoietin productivity of recombinant chinese hamster ovary cells

✍ Scribed by Joo Young Chung; Seung Wook Lim; Yeon Joo Hong; Sun Ok Hwang; Gyun Min Lee

Book ID
102762654
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
970 KB
Volume
85
Category
Article
ISSN
0006-3592

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Effect of doxycycline-regulated protein
Effect of doxycycline-regulated protein disulfide isomerase expression on the specific productivity of recombinant CHO cells: Thrombopoietin and antibody
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## Abstract Protein disulfide isomerase (PDI), one of the ER‐resident molecular chaperones, forms and isomerizes disulfide bonds. This study attempts to investigate the effect of PDI expression level on specific productivity (__q__) of recombinant Chinese hamster ovary (rCHO) cells producing thromb