During formulation design of a once-daily controlled release matrix system of divalproex sodium, the in vitro dissolution test (USP II, 100 rpm, pH 6.8 buffer) was found to result in release rates that were slower than in vivo absorption. The test method also did not sufficiently discriminate formul
Effect of docusate sodium on drug release from a controlled-release dosage form
β Scribed by Walter G. Chambliss; Robert W. Cleary; Richard Fischer; Alan B. Jones; Paul Skierkowski; W. Nicholes; Arthur H. Kibbe
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 485 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3549
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