Effect of dissolved oxygen concentration and impeller tip speed on itaconic acid production byAspergillus terreus
✍ Scribed by Yong Soo Park; Noriyasu Ohta; Mitsuyasu Okabe
- Publisher
- Springer Netherlands
- Year
- 1993
- Tongue
- English
- Weight
- 303 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0141-5492
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✦ Synopsis
Effect of aeration rate and impeller tip speed on mycelium growth and itaconic acid production was investigated in a batch culture of Aspergillus terreus IFO-6365. When impeller tip speed was 94.2 cm/set at a fixed aeration rate of 0.5 vvm, itaconic acid concentration was 3.6 and 1.6 times higher than those in the impeller tip speed of 62.8 and 125.7 cmlsec, respectively. When an oxygen-enriched air was supplied at a fixed impeller tip speed of 94.2 cm/set and dissolved oxygen concentration was maintained in the 20-60% range, both itaconic acid concentration and mycelium growth were not affected by the dissolved oxygen concentration.
Materials and Methods
Strain. Aspergillus ferreus IFO-6365 was used throughout this experiment.