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Effect of dimethyl sulphoxide on oxidative stress, activation of mitogen activated protein kinase and necrosis caused by thioacetamide in the rat liver

✍ Scribed by Terumi Kishioka; Chinatsu Iida; Kozue Fujii; Ritsuko Nagae; Yuki Onishi; Ikuyo Ichi; Shosuke Kojo

Book ID: 113586841
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 396 KB
Volume: 564
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2007.03.001

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## Abstract Oxidative stress in the brain has been increasingly associated with the development of numerous human neurological diseases. Microglia, activated upon neuronal injury or inflammatory stimulation, are known to release superoxide anion (^·^O), hydrogen peroxide (H~2~O~2~), and nitric oxid