Effect of diltiazem on the oxymyoglobin level of myocardial cells in the isolated, perfused rat heart during hypoxia
β Scribed by Hisao Matsumura; Akiyoshi Hara; Yasushi Abiko
- Publisher
- Springer US
- Year
- 1990
- Tongue
- English
- Weight
- 356 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0920-3206
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## Abstract The objective of this study was to determine the effects of repetitive ischemia on myocardial oxygen tension (pO~2~), consumption, and delivery in crystalloid normoperfused (perfuβsion pressure > 70 mmHg) and hypoperfused (perfusion pressure Λ50 mmHg) constant flow isolated rat hearts.
## Abstract Each of six perfused rat hearts was subjected to 30 min of hypoxia followed by 60 min of reoxygenation. Inversionβrecovery data on the intracellular Na NMR signal, differentiated by a shift reagent, 6 m__M__ Dy(PPP)~2~, were obtained every 5 min, and __T__~1~ values were calculated. The