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Effect of diltiazem on spontaneous cyclic Ca2+ release from sarcoplasmic reticulum

โœ Scribed by Jun Asayama; Tetsuya Tatsumi; Hiroshi Miyazaki; Itsuki Omori; Takeshi Shirayama; Daisuke Inoue; Masao Nakagawa


Book ID
115883455
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
493 KB
Volume
175
Category
Article
ISSN
0014-2999

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Regulation of Ca2+release from sarcoplas
โœ Do Han Kim; Young Sup Lee; Arthur B. Landry ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 321 KB

Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an