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Effect of dichloroacetate on acetyl-CoA content and acetylcholine synthesis in rat brain synaptosomes

✍ Scribed by A. Szutowicz; H. Bielarczyk; H. Skulimowska


Publisher
Springer
Year
1994
Tongue
English
Weight
537 KB
Volume
19
Category
Article
ISSN
0364-3190

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## Abstract Sixty percent of the dopamine β‐hydroxylase (DBH) (EC 1.14.2.1) activity in rat brain was found to be bound to membrane fractions. The additions of Triton X‐100 solubilized DBH completely and permitted the estimated of the total enzyme activity. In homogenates the DBH could be detected